Description

Atropa belladonna, commonly known as belladonna or deadly nightshade, is a toxic perennial herbaceous plant in the nightshade family Solanaceae, which also includes tomatoes, potatoes and aubergine (Eggplant). It is native to Europe and Western Asia, including Turkey. Its distribution extends from Ireland in the west to western Ukraine and the Iranian province of Gilan in the east. It is also naturalised or introduced in some parts of Canada, North Africa and the United States.

The foliage and berries are extremely toxic when ingested, containing tropane alkaloids. These toxins include atropine, scopolamine, and hyoscyamine, which cause delirium and hallucinations, and are also used as pharmaceutical anticholinergics. Tropane alkaloids are of common occurrence not only in the Old World tribes Hyoscyameae (to which the genus Atropa belongs) and Mandragoreae, but also in the New World tribe Datureae - all of which belong to the subfamily Solanoideae of the plant family Solanaceae.

Atropa belladonna has unpredictable effects. The antidote for belladonna poisoning is physostigmine or pilocarpine, the same as for atropine.

Whole Genomes

Whole Genome Sequences & Annotations for Atropa belladonna

• Atropa belladonna gwh_assembly Abe

S genes

Atropa belladonna gwh_assembly Abe S genes

Query	Chromosome	Size(bp)	Coordinates	BLASTn Hit	BLASTn %ID	Domain
SLF15	GWHBOWM00000013	46322822	42616277-42615024	Solanum tuberosum DM8.1, SLF15	82.2	F-box domain

Downloads

The Atropa belladonna S gene sequences are available in FASTA format.

CDS and Protein (FASTA file)

S-gene_Atropa_belladonna

Publications

Zhang F, Qiu F, Zeng J, Xu Z, Tang Y, Zhao T, Gou Y, Su F, Wang S, Sun X, Xue Z, Wang W, Yang C, Zeng L, Lan X, Chen M, Zhou J, Liao Z. Revealing evolution of tropane alkaloid biosynthesis by analyzing two genomes in the Solanaceae family. Nat Commun. 2023 Mar 15;14(1):1446. doi: 10.1038/s41467-023-37133-4